The 2025 Global AIDS Update, AIDS, Crisis and the Power to Transform, shows that a historic funding crisis is threatening to unravel decades of progress unless countries can make radical shifts to HIV programming and funding. The report highlights the impact that the sudden, large-scale funding cuts from international donors are having on countries most affected by HIV. Yet it also showcases some inspiring examples of resilience, with countries and communities stepping up in the face of adversity to protect the gains made and drive the HIV response forward.

This report makes clear that there is a path to end AIDS. Taking that path will help ensure preparedness to address other pandemic challenges, and advance progress across the Sustainable Development Goals. The data and real-world examples in the report make it very clear what that path is. It is not a mystery. It is a choice. Some leaders are already following the path—and succeeding. It is inspiring to note that Botswana, Eswatini, Rwanda, the United Republic of Tanzania and Zimbabwe have already achieved the 95–95–95 targets, and at least 16 other countries (including eight in sub-Saharan Africa) are close to doing so. HIV responses succeed when they are anchored in strong political leadership to follow the evidence; to tackle the inequalities holding back progress; to enable communities and civil society organizations in their vital roles in the response; and to ensure sufficient and sustainable funding. This report describes in detail how countries that put people and communities first in their policies and programmes are already leading the world on the journey to end AIDS by 2030.